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Doxycycline Enhances Survival and Self-Renewal of Human Pluripotent Stem Cells

We here report that doxycycline, an antibacterial agent, exerts dramatic effects on human embryonic stem and induced pluripotent stem cells (hESC/iPSCs) survival and self-renewal. The survival-promoting effect was also manifest in cultures of neural stem cells (NSCs) derived from hESC/iPSCs. These d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chang, Mi-Yoon, Rhee, Yong-Hee, Yi, Sang-Hoon, Lee, Su-Jae, Kim, Rae-Kwon, Kim, Hyongbum, Park, Chang-Hwan, Lee, Sang-Hun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175555/
https://ncbi.nlm.nih.gov/pubmed/25254347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.06.013
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