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TRPA1-Dependent Pruritus in IL-13-Induced Chronic Atopic Dermatitis

Chronic debilitating pruritus is a cardinal feature of a topic dermatitis (AD). Little is known about the underlying mechanisms. Antihistamines lack efficacy in treating itch in AD, suggesting the existence of histamine-independent itch pathways in AD. Transient receptor potential ankyrin 1 (TRPA1)...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Oh, Min-Hee, OH, Sun Young, Lu, Jingning, Lou, Hongfei, Myers, Allen, Zhu, Zhou, Zheng, Tao
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175413/
https://ncbi.nlm.nih.gov/pubmed/24140646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300300
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