Conformational Analysis of the Streptococcus pneumoniae Hyaluronate Lyase and Characterization of Its Hyaluronan-specific Carbohydrate-binding Module

For a subset of pathogenic microorganisms, including Streptococcus pneumoniae, the recognition and degradation of host hyaluronan contributes to bacterial spreading through the extracellular matrix and enhancing access to host cell surfaces. The hyaluronate lyase (Hyl) presented on the surface of S....

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Bibliographische Detailangaben
Hauptverfasser: Suits, Michael D. L., Pluvinage, Benjamin, Law, Adrienne, Liu, Yan, Palma, Angelina S., Chai, Wengang, Feizi, Ten, Boraston, Alisdair B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Glycobiology and Extracellular Matrices
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175358/
https://ncbi.nlm.nih.gov/pubmed/25100731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.578435
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