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Structural Analysis of a Family 101 Glycoside Hydrolase in Complex with Carbohydrates Reveals Insights into Its Mechanism

O-Linked glycosylation is one of the most abundant post-translational modifications of proteins. Within the secretory pathway of higher eukaryotes, the core of these glycans is frequently an N-acetylgalactosamine residue that is α-linked to serine or threonine residues. Glycoside hydrolases in famil...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Gregg, Katie J., Suits, Michael D. L., Deng, Lehua, Vocadlo, David J., Boraston, Alisdair B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646209/
https://ncbi.nlm.nih.gov/pubmed/26304114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.680470
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