Taste of a Pill: ORGANIC CATION TRANSPORTER-3 (OCT3) MEDIATES METFORMIN ACCUMULATION AND SECRETION IN SALIVARY GLANDS

Drug-induced taste disturbance is a common adverse drug reaction often triggered by drug secretion into saliva. Very little is known regarding the molecular mechanisms underlying salivary gland transport of xenobiotics, and most drugs are assumed to enter saliva by passive diffusion. In this study,...

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Hlavní autoři: Lee, Nora, Duan, Haichuan, Hebert, Mary F., Liang, C. Jason, Rice, Kenneth M., Wang, Joanne
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Membrane Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175343/
https://ncbi.nlm.nih.gov/pubmed/25107910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.570564
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