Taste of a Pill: ORGANIC CATION TRANSPORTER-3 (OCT3) MEDIATES METFORMIN ACCUMULATION AND SECRETION IN SALIVARY GLANDS

Drug-induced taste disturbance is a common adverse drug reaction often triggered by drug secretion into saliva. Very little is known regarding the molecular mechanisms underlying salivary gland transport of xenobiotics, and most drugs are assumed to enter saliva by passive diffusion. In this study,...

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Bibliographische Detailangaben
Hauptverfasser: Lee, Nora, Duan, Haichuan, Hebert, Mary F., Liang, C. Jason, Rice, Kenneth M., Wang, Joanne
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Membrane Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175343/
https://ncbi.nlm.nih.gov/pubmed/25107910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.570564
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