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Maternal Aldehyde Elimination during Pregnancy Preserves the Fetal Genome

Maternal metabolism provides essential nutrients to enable embryonic development. However, both mother and embryo produce reactive metabolites that can damage DNA. Here we discover how the embryo is protected from these genotoxins. Pregnant mice lacking Aldh2, a key enzyme that detoxifies reactive a...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Oberbeck, Nina, Langevin, Frédéric, King, Gareth, de Wind, Niels, Crossan, Gerry P., Patel, Ketan J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Cell Press 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175174/
https://ncbi.nlm.nih.gov/pubmed/25155611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.07.010
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