Maternal Aldehyde Elimination during Pregnancy Preserves the Fetal Genome

Maternal metabolism provides essential nutrients to enable embryonic development. However, both mother and embryo produce reactive metabolites that can damage DNA. Here we discover how the embryo is protected from these genotoxins. Pregnant mice lacking Aldh2, a key enzyme that detoxifies reactive a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Oberbeck, Nina, Langevin, Frédéric, King, Gareth, de Wind, Niels, Crossan, Gerry P., Patel, Ketan J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cell Press 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175174/
https://ncbi.nlm.nih.gov/pubmed/25155611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.07.010
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