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The role of post-translational modifications in fine-tuning BLM helicase function during DNA repair
RecQ-like helicases are a highly conserved family of proteins which are critical for preserving genome integrity. Genome instability is considered a hallmark of cancer and mutations within three of the five human RECQ genes cause hereditary syndromes that are associated with cancer predisposition. T...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4175148/ https://ncbi.nlm.nih.gov/pubmed/25150915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2014.07.007 |
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