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The role of post-translational modifications in fine-tuning BLM helicase function during DNA repair

RecQ-like helicases are a highly conserved family of proteins which are critical for preserving genome integrity. Genome instability is considered a hallmark of cancer and mutations within three of the five human RECQ genes cause hereditary syndromes that are associated with cancer predisposition. T...

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Bibliografski detalji
Glavni autori: Böhm, Stefanie, Bernstein, Kara Anne
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175148/
https://ncbi.nlm.nih.gov/pubmed/25150915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2014.07.007
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