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Genome Engineering with TALENs and ZFNs: Repair pathways and donor design
Genome engineering with targetable nucleases depends on cellular pathways of DNA repair after target cleavage. Knowledge of how those pathways work, their requirements and their active factors, can guide experimental design and improve outcomes. While many aspects of both homologous recombination (H...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4175112/ https://ncbi.nlm.nih.gov/pubmed/24704173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2014.03.026 |
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