Investigation of novel circulating proteins, germ line single-nucleotide polymorphisms, and molecular tumor markers as potential efficacy biomarkers of first-line sunitinib therapy for advanced renal cell carcinoma

PURPOSE: Sunitinib is a first-line advanced renal cell carcinoma (RCC) standard of care. In a randomized phase II trial comparing sunitinib treatment schedules, separate exploratory biomarker analyses investigated the correlations of efficacy with selected serum, germ line single-nucleotide polymorp...

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Bibliografiska uppgifter
Huvudupphovsmän: Motzer, Robert J., Hutson, Thomas E., Hudes, Gary R., Figlin, Robert A., Martini, Jean-Francois, English, Patricia A., Huang, Xin, Valota, Olga, Williams, J. Andrew
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer Berlin Heidelberg 2014
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Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175044/
https://ncbi.nlm.nih.gov/pubmed/25100134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-014-2539-0
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