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RNA-protein interactions in unstable microsatellite diseases

A novel RNA-mediated disease mechanism has emerged from studies on dominantly inherited neurological disorders caused by unstable microsatellite expansions in non-coding regions of the genome. These non-coding tandem repeat expansions trigger the production of unusual RNAs that gain a toxic function...

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Detalhes bibliográficos
Main Authors: Mohan, Apoorva, Goodwin, Marianne, Swanson, Maurice S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174988/
https://ncbi.nlm.nih.gov/pubmed/24709120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2014.03.039
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