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Downregulation of MicroRNA-21 is Involved in the Propofol-Induced Neurotoxicity Observed in Human Stem Cell-Derived Neurons

BACKGROUND: Recent studies in various animal models have suggested that anesthetics such as propofol, when administered early in life, can lead to neurotoxicity. These studies have raised significant safety concerns regarding the use of anesthetics in the pediatric population and highlight the need...

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Main Authors: Twaroski, Danielle M., Yan, Yasheng, Olson, Jessica M., Bosnjak, Zeljko J., Bai, Xiaowen
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174986/
https://ncbi.nlm.nih.gov/pubmed/24950164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000345
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