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Downregulation of MicroRNA-21 is Involved in the Propofol-Induced Neurotoxicity Observed in Human Stem Cell-Derived Neurons

BACKGROUND: Recent studies in various animal models have suggested that anesthetics such as propofol, when administered early in life, can lead to neurotoxicity. These studies have raised significant safety concerns regarding the use of anesthetics in the pediatric population and highlight the need...

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Detalhes bibliográficos
Main Authors: Twaroski, Danielle M., Yan, Yasheng, Olson, Jessica M., Bosnjak, Zeljko J., Bai, Xiaowen
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174986/
https://ncbi.nlm.nih.gov/pubmed/24950164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000345
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