טוען...
Potentiated Hsp104 variants suppress toxicity of diverse neurodegenerative disease-linked proteins
Protein misfolding is implicated in numerous lethal neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS) and Parkinson disease (PD). There are no therapies that reverse these protein-misfolding events. We aim to apply Hsp104, a hexameric AAA+ protein from yeast, to target misfo...
שמור ב:
| Main Authors: | , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
The Company of Biologists Limited
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4174528/ https://ncbi.nlm.nih.gov/pubmed/25062688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.016113 |
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