Triazole-containing monophosphate mRNA cap analogs as effective translation inhibitors

Synthetic analogs of the 5′ end of mRNA (cap structure) are widely used in molecular studies on mechanisms of cellular processes such as translation, intracellular transport, splicing, and turnover. The best-characterized cap binding protein is translation initiation factor 4E (eIF4E). Recognition o...

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Bibliografiske detaljer
Main Authors: Piecyk, Karolina, Lukaszewicz, Maciej, Darzynkiewicz, Edward, Jankowska-Anyszka, Marzena
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2014
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Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174436/
https://ncbi.nlm.nih.gov/pubmed/25150228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.046193.114
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