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De novo translation initiation on membrane-bound ribosomes as a mechanism for localization of cytosolic protein mRNAs to the endoplasmic reticulum

The specialized protein synthesis functions of the cytosol and endoplasmic reticulum compartments are conferred by the signal recognition particle (SRP) pathway, which directs the cotranslational trafficking of signal sequence-encoding mRNAs from the cytosol to the endoplasmic reticulum (ER). Althou...

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Autors principals: Jagannathan, Sujatha, Reid, David W., Cox, Amanda H., Nicchitta, Christopher V.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174431/
https://ncbi.nlm.nih.gov/pubmed/25142066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.045526.114
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