Heterogeneous translational landscape of the endoplasmic reticulum revealed by ribosome proximity labeling and transcriptome analysis

The endoplasmic reticulum (ER) is a nexus for mRNA localization and translation, and recent studies have demonstrated that ER-bound ribosomes also play a transcriptome-wide role in regulating proteome composition. The Sec61 translocon (SEC61) serves as the receptor for ribosomes that translate secre...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Hoffman, Alyson M., Chen, Qiang, Zheng, Tianli, Nicchitta, Christopher V.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2019
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552412/
https://ncbi.nlm.nih.gov/pubmed/31004035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007996
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