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The N-terminal region (A/B) of rat thyroid hormone receptors alpha 1, beta 1, but not beta 2 contains a strong thyroid hormone-dependent transactivation function.

In this study we have investigated the role of the N-terminal region of thyroid hormone receptors (TRs) in thyroid hormone (TH)-dependent transactivation of a thymidine kinase promoter containing TH response elements composed either of a direct repeat or an inverted palindrome. Comparison of rat TR...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Tomura, H, Lazar, J, Phyillaier, M, Nikodem, V M
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1995
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41744/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7539921/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.12.5600
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