The ligand-binding domains of the thyroid hormone/retinoid receptor gene subfamily function in vivo to mediate heterodimerization, gene silencing, and transactivation.

The ligand-binding domains (LBDs) of the thyroid/retinoid receptor gene subfamily contain a series of heptad motifs important for dimeric interactions. This subfamily includes thyroid hormone receptors (T3Rs), all-trans retinoic acid (RA) receptors (RARs), 9-cis RA receptors (RARs and retinoid X rec...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Qi, J S, Desai-Yajnik, V, Greene, M E, Raaka, B M, Samuels, H H
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1995
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC230406/
https://ncbi.nlm.nih.gov/pubmed/7862171
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi