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Immunologic hierarchy, class II MHC promiscuity, and epitope spreading of a melanoma helper peptide vaccine

Immunization with a combination melanoma helper peptide (6MHP) vaccine has been shown to induce CD4(+) T cell responses, which are associated with patient survival. In the present study, we define the relative immunogenicity and HLA allele promiscuity of individual helper peptides and identify helpe...

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Bibliografiske detaljer
Main Authors: Hu, Yinin, Petroni, Gina R., Olson, Walter C., Czarkowski, Andrea, Smolkin, Mark E., Grosh, William W., Chianese-Bullock, Kimberly A., Slingluff, Craig L.
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174310/
https://ncbi.nlm.nih.gov/pubmed/24756419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-014-1551-x
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