Ceruloplasmin potentiates nitric oxide synthase activity and cytokine secretion in activated microglia

BACKGROUND: Ceruloplasmin is a ferroxidase expressed in the central nervous system both as soluble form in the cerebrospinal fluid (CSF) and as membrane-bound GPI-anchored isoform on astrocytes, where it plays a role in iron homeostasis and antioxidant defense. It has been proposed that ceruloplasmi...

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Main Authors: Lazzaro, Massimo, Bettegazzi, Barbara, Barbariga, Marco, Codazzi, Franca, Zacchetti, Daniele, Alessio, Massimo
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174266/
https://ncbi.nlm.nih.gov/pubmed/25224679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-014-0164-9
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