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Ceruloplasmin potentiates nitric oxide synthase activity and cytokine secretion in activated microglia
BACKGROUND: Ceruloplasmin is a ferroxidase expressed in the central nervous system both as soluble form in the cerebrospinal fluid (CSF) and as membrane-bound GPI-anchored isoform on astrocytes, where it plays a role in iron homeostasis and antioxidant defense. It has been proposed that ceruloplasmi...
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Hauptverfasser: | , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
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BioMed Central
2014
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4174266/ https://ncbi.nlm.nih.gov/pubmed/25224679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-014-0164-9 |
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