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The effect of bromine scanning around the phenyl group of 4-phenyl­quinolone derivatives

Three quinolone compounds were synthesized and crystallized in an effort to study the structure–activity relationship of these calcium-channel antagonists. In all three quinolones, viz. ethyl 4-(4-bromo­phenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexa­hydro­quinoline-3-carboxyl­ate, (I), ethyl 4-(3-br...

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Autors principals: Steiger, Scott A., Monacelli, Anthony J., Li, Chun, Hunting, Janet L., Natale, Nicholas R.
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174017/
https://ncbi.nlm.nih.gov/pubmed/25093361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053229614015617
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