Macrophage-derived apoE(Sendai) suppresses atherosclerosis while causing lipoprotein glomerulopathy in hyperlipidemic mice

Lipoprotein glomerulopathy (LPG) is a renal disease often accompanied by dyslipidemia and increased serum apoE levels. apoE(Sendai) (Arg145Pro), a rare mutant based on the apoE3 sequence carrying an apoE2 charge, causes LPG in humans and transgenic mice, but its effects on the artery wall are unknow...

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Bibliografiska uppgifter
Huvudupphovsmän: Tavori, Hagai, Fan, Daping, Giunzioni, Ilaria, Zhu, Lin, Linton, MacRae F., Fogo, Agnes B., Fazio, Sergio
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Biochemistry and Molecular Biology 2014
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174000/
https://ncbi.nlm.nih.gov/pubmed/25183802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M049874
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