A randomised trial of ondansetron for the treatment of irritable bowel syndrome with diarrhoea

BACKGROUND: Irritable bowel syndrome with diarrhoea (IBS-D) is particularly debilitating due to urgency and episodic incontinence. Some 5-hydroxytryptamine 3 (5-HT3) receptor antagonists (5-HT3RAs) have proven effective but have serious side effects. Ondansetron, also a 5-HT3RA, has been widely used...

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Main Authors: Garsed, Klara, Chernova, Julia, Hastings, Margaret, Lam, Ching, Marciani, Luca, Singh, Gulzar, Henry, Amanda, Hall, Ian, Whorwell, Peter, Spiller, Robin
Format: Artigo
Jezik:Inglês
Izdano: BMJ Publishing Group 2014
Teme:
Neurogastroenterology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4173656/
https://ncbi.nlm.nih.gov/pubmed/24334242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2013-305989
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