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A prominent and conserved role for YY1 in Xist transcriptional activation
Accumulation of the non-coding RNA Xist on one X chromosome in female cells is a hallmark of X-chromosome inactivation in eutherians. Here, we uncovered an essential function for the ubiquitous autosomal transcription factor Yin-Yang 1 (YY1) in the transcriptional activation of Xist in both human an...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4172967/ https://ncbi.nlm.nih.gov/pubmed/25209548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5878 |
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