Modeling interactions between Human Equilibrative Nucleoside Transporter-1 and other factors involved in the response to gemcitabine treatment to predict clinical outcomes in pancreatic ductal adenocarcinoma patients

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive malignancy, characterized by largely unsatisfactory responses to the currently available therapeutic strategies. In this study we evaluated the expression of genes involved in gemcitabine uptake in a selected cohort of pa...

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Hauptverfasser: Tavano, Francesca, Fontana, Andrea, Pellegrini, Fabio, Burbaci, Francesca Paola, Rappa, Francesca, Cappello, Francesco, Copetti, Massimiliano, Maiello, Evaristo, Lombardi, Lucia, Graziano, Paolo, Vinciguerra, Manlio, di Mola, Fabio Francesco, di Sebastiano, Pierluigi, Andriulli, Angelo, Pazienza, Valerio
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172900/
https://ncbi.nlm.nih.gov/pubmed/25199538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-014-0248-4
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