Modeling interactions between Human Equilibrative Nucleoside Transporter-1 and other factors involved in the response to gemcitabine treatment to predict clinical outcomes in pancreatic ductal adenocarcinoma patients

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive malignancy, characterized by largely unsatisfactory responses to the currently available therapeutic strategies. In this study we evaluated the expression of genes involved in gemcitabine uptake in a selected cohort of pa...

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Detalhes bibliográficos
Main Authors: Tavano, Francesca, Fontana, Andrea, Pellegrini, Fabio, Burbaci, Francesca Paola, Rappa, Francesca, Cappello, Francesco, Copetti, Massimiliano, Maiello, Evaristo, Lombardi, Lucia, Graziano, Paolo, Vinciguerra, Manlio, di Mola, Fabio Francesco, di Sebastiano, Pierluigi, Andriulli, Angelo, Pazienza, Valerio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172900/
https://ncbi.nlm.nih.gov/pubmed/25199538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-014-0248-4
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