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Genetic variation in taste receptor pseudogenes provides evidence for a dynamic role in human evolution

BACKGROUND: Human bitter taste receptors are encoded by a gene family consisting of 25 functional TAS2R loci. In addition, humans carry 11 TAS2R pseudogenes, some of which display evidence for substantial diversification among species, showing lineage-specific loss of function. Since bitter taste is...

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Hlavní autoři: Risso, Davide, Tofanelli, Sergio, Morini, Gabriella, Luiselli, Donata, Drayna, Dennis
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172856/
https://ncbi.nlm.nih.gov/pubmed/25216916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12862-014-0198-8
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