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3′-Deoxy-3′-[(18)F]-Fluorothymidine PET Imaging Reflects PI3K-mTOR-Mediated Pro-Survival Response to Targeted Therapy in Colorectal Cancer

Biomarkers that predict response to targeted therapy in oncology are an essential component of personalized medicine. In preclinical treatment response studies that featured models of wild-type KRAS or mutant BRAF colorectal cancer treated with either cetuximab or vemurafenib, respectively, we illus...

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Bibliografische gegevens
Hoofdauteurs: McKinley, Eliot T., Zhao, Ping, Coffey, Robert J., Washington, M. Kay, Manning, H. Charles
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172755/
https://ncbi.nlm.nih.gov/pubmed/25247710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108193
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