Constitutive androstane receptor agonist, TCPOBOP, attenuates steatohepatitis in the methionine choline-deficient diet-fed mouse

AIM: To ascertain whether constitutive androstane receptor (CAR) activation by 1,4-bis-[2-(3,5,-dichloropyridyloxy)] benzene (TCPOBOP) modulates steatohepatitis in the methionine choline-deficient (MCD) diet-fed animal. METHODS: C57/BL6 wild-type mice were fed the MCD or standard diet for 2 wk and w...

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Autores principales: Baskin-Bey, Edwina S, Anan, Akira, Isomoto, Hajime, Bronk, Steven F, Gores, Gregory J
Formato: Artigo
Lenguaje:Inglês
Publicado: Baishideng Publishing Group Inc 2007
Materias:
Rapid Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172744/
https://ncbi.nlm.nih.gov/pubmed/17948939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v13.i42.5635
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