Effect of developmental stage of HSC and recipient on transplant outcomes

The first hematopoietic stem cells (HSCs) that engraft irradiated adult mice arise in the aortagonad-mesonephros (AGM) on embryonic day 11.5 (E11.5). However, at this stage there is a discrepancy between the apparent frequency of HSCs suggested by imaging and their rarity when measured by limiting d...

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Detalhes bibliográficos
Main Authors: Arora, Natasha, Wenzel, Pamela L., McKinney-Freeman, Shannon L., Ross, Samantha J., Kim, Peter G., Chou, Stephanie S., Yoshimoto, Momoko, Yoder, Mervin C., Daley, George Q.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172398/
https://ncbi.nlm.nih.gov/pubmed/24914562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.04.013
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