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Accounting for linkage disequilibrium in genome-wide association studies: A penalized regression method
Penalized regression methods are becoming increasingly popular in genome-wide association studies (GWAS) for identifying genetic markers associated with disease. However, standard penalized methods such as LASSO do not take into account the possible linkage disequilibrium between adjacent markers. W...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4172344/ https://ncbi.nlm.nih.gov/pubmed/25258655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4310/SII.2013.v6.n1.a10 |
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