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Accounting for linkage disequilibrium in genome-wide association studies: A penalized regression method

Penalized regression methods are becoming increasingly popular in genome-wide association studies (GWAS) for identifying genetic markers associated with disease. However, standard penalized methods such as LASSO do not take into account the possible linkage disequilibrium between adjacent markers. W...

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Detalhes bibliográficos
Main Authors: Liu, Jin, Wang, Kai, Ma, Shuangge, Huang, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172344/
https://ncbi.nlm.nih.gov/pubmed/25258655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4310/SII.2013.v6.n1.a10
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