Fc receptor is not required for inducing antibodies but plays a critical role in conferring protection after influenza M2 vaccination

The ectodomain of matrix protein 2 (M2e) of influenza virus is considered a rational target for a universal influenza A vaccine. To better understand M2e immune-mediated protection, Fc receptor common γ chain deficient (FcRγ(−/−)) and wild-type mice were immunized with a tandem repeat of M2e present...

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Autores principales: Lee, Yu-Na, Lee, Young-Tae, Kim, Min-Chul, Hwang, Hye Suk, Lee, Jong Seok, Kim, Ki-Hye, Kang, Sang-Moo
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2014
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172145/
https://ncbi.nlm.nih.gov/pubmed/24773389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12310
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