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l-Arginine modulates neonatal lymphocyte proliferation through an interleukin-2 independent pathway

In cases of arginine depletion, lymphocyte proliferation, cytokine production and CD3ζ chain expression are all diminished. In addition to myeloid suppressor cells, polymorphonuclear cells (PMN) also exert T-cell immune suppressive effects through arginase-induced l-arginine depletion, especially du...

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Bibliografische gegevens
Hoofdauteurs: Yu, Hong-Ren, Kuo, Ho-Chang, Huang, Li-Tung, Chen, Chih-Cheng, Tain, You-Lin, Sheen, Jiunn-Ming, Tiao, Mao-Meng, Huang, Hsin-Chun, Yang, Kuender D, Ou, Chia-Yo, Hsu, Te-Yao
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Science Inc 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172135/
https://ncbi.nlm.nih.gov/pubmed/24697328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12300
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