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l-Arginine modulates neonatal lymphocyte proliferation through an interleukin-2 independent pathway
In cases of arginine depletion, lymphocyte proliferation, cytokine production and CD3ζ chain expression are all diminished. In addition to myeloid suppressor cells, polymorphonuclear cells (PMN) also exert T-cell immune suppressive effects through arginase-induced l-arginine depletion, especially du...
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| Hauptverfasser: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Science Inc
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4172135/ https://ncbi.nlm.nih.gov/pubmed/24697328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12300 |
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