Synthetic Lethality Reveals Mechanisms of Mycobacterium tuberculosis Resistance to β-Lactams

Most β-lactam antibiotics are ineffective against Mycobacterium tuberculosis due to the microbe’s innate resistance. The emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains has prompted interest to repurpose this class of drugs. To identify the genetic determinants of...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Lun, Shichun, Miranda, David, Kubler, Andre, Guo, Haidan, Maiga, Mariama C., Winglee, Kathryn, Pelly, Shaaretha, Bishai, William R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Microbiology 2014
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172077/
https://ncbi.nlm.nih.gov/pubmed/25227469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01767-14
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi