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Synthesis of (+)-Discodermolide by Catalytic Stereoselective Borylation Reactions()

The marine natural product (+)-discodermolide was first isolated in 1990 and, to this day, remains a compelling synthesis target. Not only does the compound possess fascinating biological activity, but it also presents an opportunity to test current methods for chemical synthesis and provides a foru...

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Autori principali: Yu, Zhiyong, Ely, Robert J., Morken, James P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171733/
https://ncbi.nlm.nih.gov/pubmed/25045037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201405455
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