Markers of cellular senescence are elevated in murine blastocysts cultured in vitro: molecular consequences of culture in atmospheric oxygen

PURPOSE: We aimed to determine whether embryo culture induces markers of cellular senescence and whether these effects were dependent on culture conditions. METHODS: Murine blastocysts were derived in vitro and in vivo and assessed for 2 primary markers of senescence: senescence-associated β-galacto...

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Bibliografiske detaljer
Main Authors: Meuter, Alexandra, Rogmann, Lisa-Marlen, Winterhoff, Boris J., Tchkonia, Tamar, Kirkland, James L., Morbeck, Dean E.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2014
Fag:
Embryo Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171413/
https://ncbi.nlm.nih.gov/pubmed/25106938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-014-0299-8
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