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Exogenous sphingomyelinase causes impaired intestinal epithelial barrier function

AIM: To test the hypothesis that hydrolysis of sphingomyelin to ceramide changes the composition of tight junctions (TJs) with increasing permeability of the intestinal epithelium. METHODS: Monolayers of Caco-2 cells were used as an in vitro model for the intestinal barrier. Permeability was determi...

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Detalhes bibliográficos
Main Authors: Bock, Jürgen, Liebisch, Gerhard, Schweimer, Joachim, Schmitz, Gerd, Rogler, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171303/
https://ncbi.nlm.nih.gov/pubmed/17876892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v13.i39.5217
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