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c-Jun NH2-terminal kinase-induced proteasomal degradation of c-FLIP(L/S) and Bcl(2) sensitize prostate cancer cells to Fas- and mitochondria-mediated apoptosis by tetrandrine
Tetrandrine, a constituent of Chinese herb Stephania tetrandra, causes cell death in prostate cancer, but the molecular mechanisms leading to apoptosis is not known. Here we demonstrated that tetrandrine selectively inhibits the growth of prostate cancer PC3 and DU145 cells compared to normal prosta...
Tallennettuna:
| Päätekijät: | , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4171211/ https://ncbi.nlm.nih.gov/pubmed/25181458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2014.08.014 |
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