TIMP-1 via TWIST1 Induces EMT Phenotypes in Human Breast Epithelial Cells

Tissue inhibitor of metalloproteinase-1 (TIMP1) regulates intracellular signaling networks for inhibition of apoptosis. Tetraspanin (CD63), a cell surface binding partner for TIMP-1, was previously shown to regulate integrin-mediated survival pathways in the human breast epithelial cell line MCF10A....

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Hauptverfasser: D’Angelo, Rosemarie Chirco, Liu, Xu-Wen, Najy, Abdo J., Jung, Young Suk, Won, Joshua, Chai, Karl X., Fridman, Rafael, Kim, Hyeong-Reh Choi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171133/
https://ncbi.nlm.nih.gov/pubmed/24895412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-14-0105
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