ImmunoPET and biodistribution with human epidermal growth factor receptor 3 targeting antibody (89)Zr-RG7116

The humanized monoclonal antibody with high affinity for the human epidermal growth factor receptor (HER) 3, RG7116, is a glycoengineered, IgG1 class antibody. By labeling RG7116 with zirconium-89 ((89)Zr) we aimed to visualize in vivo HER3 expression and study the biodistribution of this antibody i...

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Autors principals: Terwisscha van Scheltinga, Anton GT, Lub-de Hooge, Marjolijn N, Abiraj, Keelara, Schröder, Carolien P, Pot, Linda, Bossenmaier, Birgit, Thomas, Marlene, Hölzlwimmer, Gabriele, Friess, Thomas, Kosterink, Jos GW, de Vries, Elisabeth GE
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171008/
https://ncbi.nlm.nih.gov/pubmed/24870719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.29097
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