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Translational termination efficiency in mammals is influenced by the base following the stop codon.

The base following stop codons in mammalian genes is strongly biased, suggesting that it might be important for the termination event. This proposal has been tested experimentally both in vivo by using the human type I iodothyronine deiodinase mRNA and the recoding event at the internal UGA codon an...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: McCaughan, K K, Brown, C M, Dalphin, M E, Berry, M J, Tate, W P
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41708/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7777525/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.12.5431
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