Stop codon context influences genome-wide stimulation of termination codon readthrough by aminoglycosides
Stop codon readthrough (SCR) occurs when the ribosome miscodes at a stop codon. Such readthrough events can be therapeutically desirable when a premature termination codon (PTC) is found in a critical gene. To study SCR in vivo in a genome-wide manner, we treated mammalian cells with aminoglycosides...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
eLife Sciences Publications Ltd
2020-01-01
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| Col·lecció: | eLife |
| Matèries: | |
| Accés en línia: | https://elifesciences.org/articles/52611 |
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