Estradiol negatively modulates the pleiotropic actions of orphanin FQ/nociceptin at proopiomelanocortin synapses

Orphanin FQ/nociceptin (OFQ/N) inhibits the activity of proopiomelanocortin (POMC) neurons located in the hypothalamic arcuate nucleus (ARH) that regulate female sexual behavior and energy balance. We tested the hypothesis that estradiol modulates the ability of OFQ/N to presynaptically and postsyna...

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Bibliographic Details
Main Authors: Borgquist, Amanda, Kachani, Malika, Tavitian, Nadia, Sinchak, Kevin, Wagner, Edward J.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170741/
https://ncbi.nlm.nih.gov/pubmed/23735696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000351868
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