Specific delivery of microRNA93 into HBV-replicating hepatocytes downregulates protein expression of liver cancer susceptible gene MICA

Chronic hepatitis B virus (HBV) infection is a major cause of hepatocellular carcinoma (HCC). To date, the lack of efficient in vitro systems supporting HBV infection and replication has been a major limitation of HBV research. Although primary human hepatocytes support the complete HBV life cycle,...

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Detalhes bibliográficos
Main Authors: Ohno, Motoko, Otsuka, Motoyuki, Kishikawa, Takahiro, Shibata, Chikako, Yoshikawa, Takeshi, Takata, Akemi, Muroyama, Ryosuke, Kowatari, Norie, Sato, Masaya, Kato, Naoya, Kuroda, Shun'ichi, Koike, Kazuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170619/
https://ncbi.nlm.nih.gov/pubmed/25026299
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